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Rabbit anti-Human SLC39A4 Polyclonal Antibody

The antibody against SLC39A4 was raised in rabbit using the Human SLC39A4 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

ADC-51830A

The antibody against SLC39A4 was raised in rabbit using the Human SLC39A4 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

$600.00

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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ADC-51830A ClonalityPolyclonal
Host SpeciesRabbitTarget NameSLC39A4
Target SynonymsSLC39A4; ZIP4; Zinc transporter ZIP4; Solute carrier family 39 member 4; Zrt- and Irt-like protein 4; ZIP-4FormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium AzidePurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman SLC39A4Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ6P5W5
Background Information
  • Uniprot Id

    Q6P5W5

  • Target Species

    Human

  • Target Name

    SLC39A4

  • Target Full Name

    Zinc transporter ZIP4

  • Target Function

    Plays an important role in cellular zinc homeostasis as a zinc transporter. Regulated in response to zinc availability.

  • Target Involvement

    Acrodermatitis enteropathica, zinc-deficiency type (AEZ)

  • Target Subcellular Location

    Cell membrane; Multi-pass membrane protein. Recycling endosome membrane; Multi-pass membrane protein. Note=Colocalized with TFRC in the recycling endosomes. Cycles between endosomal compartments and the plasma membrane in response to zinc availability.

  • Target Protein Families

    ZIP transporter (TC 2.A.5) family

  • Target Tissue Specificity

    Highly expressed in kidney, small intestine, stomach, colon, jejunum and duodenum.

  • Target Synonyms

    SLC39A4; ZIP4; Zinc transporter ZIP4; Solute carrier family 39 member 4; Zrt- and Irt-like protein 4; ZIP-4

  • Target Background

    This gene encodes a member of the zinc/iron-regulated transporter-like protein (ZIP) family. The encoded protein localizes to cell membranes and is required for zinc uptake in the intestine. Mutations in this gene result in acrodermatitis enteropathica. Multiple transcript variants encoding different isoforms have been found for this gene.

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