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The antibody against NEMF was raised in rabbit using the Human SDCCAG1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against NEMF was raised in rabbit using the Human SDCCAG1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$600.00
| Cat.No | ADC-51940A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NEMF |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Human SDCCAG1 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O60524 |
Uniprot Id
O60524
Target Species
Human
Target Name
NEMF
Target Full Name
Ribosome quality control complex subunit NEMF
Target Function
Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. NEMF is responsible for selective recognition of stalled 60S subunits by recognizing an exposed, nascent chain-conjugated tRNA moiety. NEMF is important for the stable association of LTN1 to the complex. May indirectly play a role in nuclear export.
Target Subcellular Location
Nucleus.
Target Protein Families
NEMF family
Target Tissue Specificity
Expressed in brain, heart, liver, lung, spleen, and skeletal muscle. Also expressed at lower levels in stomach and testis.
Target Synonyms
1500011I12Rik; 4933405E14Rik; Antigen NY-CO-1; FLJ10051 ; Nemf; NEMF_HUMAN; Nuclear export mediator factor Nemf; NY CO 1; SDCCAG1; SDCG1; Serologically defined colon cancer antigen 1
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