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The antibody against MTMR8 was raised in rabbit using the Human MTMR8 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against MTMR8 was raised in rabbit using the Human MTMR8 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-52667A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MTMR8 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Human MTMR8 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96EF0 |
Uniprot Id
Q96EF0
Target Species
Human
Target Name
MTMR8
Target Full Name
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR8
Target Function
Phosphatase that acts on lipids with a phosphoinositol headgroup. Has phosphatase activity towards phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate. In complex with MTMR9, negatively regulates autophagy.
Target Subcellular Location
Nucleus envelope.
Target Protein Families
Protein-tyrosine phosphatase family, Non-receptor class myotubularin subfamily
Target Synonyms
C8orf9; DKFZP434K171; FLJ20126; LIP STYX; MTMR8; MTMR8_HUMAN; MTMR9; Myotubularin related protein 8; Myotubularin related protein 9; Myotubularin-related protein 8
Target Background
This gene encodes a member of the myotubularin-related family and is part of the MTMR6 subgroup. Family members are dual-specificity phosphatases and the encoded protein contains a phosphoinositide-binding domain (PID) and a SET-interacting domain (SID). Defects in other family members have been found in myotubular myopathic diseases.
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