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The antibody against HGSNAT was raised in rabbit using the Human HGSNAT as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against HGSNAT was raised in rabbit using the Human HGSNAT as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$600.00
| Cat.No | ADC-53132A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | HGSNAT |
| Target Synonyms | HGSNAT antibody; TMEM76 antibody; Heparan-alpha-glucosaminide N-acetyltransferase antibody; EC 2.3.1.78 antibody; Transmembrane protein 76 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Human HGSNAT | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q68CP4 |
Uniprot Id
Q68CP4
Target Species
Human
Target Name
HGSNAT
Target Full Name
Heparan-alpha-glucosaminide N-acetyltransferase
Target Function
Lysosomal acetyltransferase that acetylates the non-reducing terminal alpha-glucosamine residue of intralysosomal heparin or heparan sulfate, converting it into a substrate for luminal alpha-N-acetyl glucosaminidase.
Target Involvement
Mucopolysaccharidosis 3C (MPS3C); Retinitis pigmentosa 73 (RP73)
Target Subcellular Location
Lysosome membrane; Multi-pass membrane protein. Note=Colocalizes with the lysosomal marker LAMP2. The signal peptide is not cleaved upon translocation into the endoplasmic reticulum; the precursor is probably targeted to the lysosomes via the adapter protein complex-mediated pathway that involves tyrosine- and/or dileucine-based conserved amino acid motifs in the last C-terminus 16-amino acid domain.
Target Tissue Specificity
Widely expressed, with highest level in leukocytes, heart, liver, skeletal muscle, lung, placenta and liver.
Target Synonyms
HGSNAT; TMEM76; Heparan-alpha-glucosaminide N-acetyltransferase; EC 2.3.1.78; Transmembrane protein 76
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