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Rabbit anti-Human B3GALNT2 Polyclonal Antibody

The antibody against B3GALNT2 was raised in rabbit using the Human B3GALNT2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

ADC-54018A

The antibody against B3GALNT2 was raised in rabbit using the Human B3GALNT2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

$600.00

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Specifications


Cat.No ADC-54018A ClonalityPolyclonal
Host SpeciesRabbitTarget NameB3GALNT2
Target Synonyms3 galactosaminyltransferase 2 antibody; Beta 1, 3 galactosaminyltransferase polypeptide 2 antibody; UDP-GalNAc:beta-1 antibody; UDP-GalNAc:beta-1, 3 N acetylgalactosaminyltransferase 2 antibody; Beta 1, 3 N acetylgalactosaminyltransferase II antibody; Beta 1, 3 N acetylgalactosaminyltransferase II MGC39558 antibody; Beta 3 GalNAc T2 antibody; Beta-1 antibody; beta-1, 3-GalNAc-T2 antibody; Beta3GalNAcT2 antibody; MDDGA11 antibody; MGC39558 antibody; UDP GalNAc:betaGlcNAc beta 1, 3-N-acetylgalactosaminyltransferase 2 antibodyFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azidePurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman B3GALNT2Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ8NCR0
Background Information
  • Uniprot Id

    Q8NCR0

  • Target Species

    Human

  • Target Name

    B3GALNT2

  • Target Full Name

    UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2

  • Target Function

    Beta-1,3-N-acetylgalactosaminyltransferase that synthesizes a unique carbohydrate structure, GalNAc-beta-1-3GlcNAc, on N- and O-glycans. Has no galactose nor galactosaminyl transferase activity toward any acceptor substrate. Involved in alpha-dystroglycan (DAG1) glycosylation: acts coordinately with GTDC2/POMGnT2 to synthesize a GalNAc-beta3-GlcNAc-beta-terminus at the 4-position of protein O-mannose in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan, which is required for binding laminin G-like domain-containing extracellular proteins with high affinity.

  • Target Involvement

    Muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies A11 (MDDGA11)

  • Target Subcellular Location

    Golgi apparatus membrane; Single-pass type II membrane protein. Endoplasmic reticulum.

  • Target Protein Families

    Glycosyltransferase 31 family

  • Target Tissue Specificity

    Expressed in all tissues examined, but at highest levels in testis, adipose tissue, skeletal muscle and ovary.

  • Target Synonyms

    3-GalNAc-T2; 3-N-acetylgalactosaminyltransferase 2; 3-N-acetylgalactosaminyltransferase II; B3GalNAc T2; B3GalNAcT2; b3galnt2; B3GL2_HUMAN; Beta 1,3 galactosaminyltransferase 2; Beta 1,3 N acetylgalactosaminyltransferase 2; Beta 1,3 N acetylgalactosaminyltransferase II; Beta 1,3 N acetylgalactosaminyltransferase II MGC39558; Beta 3 GalNAc T2; Beta-1; beta-1,3-GalNAc-T2; Beta3GalNAcT2; MDDGA11; MGC39558; UDP GalNAc:betaGlcNAc beta 1,3 galactosaminyltransferase polypeptide 2; UDP-GalNAc:beta-1; UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2

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