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The antibody against OLFM4 was raised in rabbit using the Recombinant Human Olfactomedin-4 protein (224-334AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against OLFM4 was raised in rabbit using the Recombinant Human Olfactomedin-4 protein (224-334AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
$299.00
| Cat.No | ADC-06533A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | OLFM4 |
| Form | Liquid | Species Reactivity | Human, Rat |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Olfactomedin-4 protein (224-334AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q6UX06 |
Uniprot Id
Q6UX06
Target Species
Human
Target Name
OLFM4
Target Full Name
Olfactomedin-4
Target Function
May promote proliferation of pancreatic cancer cells by favoring the transition from the S to G2/M phase. In myeloid leukemic cell lines, inhibits cell growth and induces cell differentiation and apoptosis. May play a role in the inhibition of EIF4EBP1 phosphorylation/deactivation. Facilitates cell adhesion, most probably through interaction with cell surface lectins and cadherin.
Target Subcellular Location
Secreted, extracellular space. Mitochondrion.
Target Tissue Specificity
Expressed during myeloid lineage development. Much higher expression in bone marrow neutrophils than in peripheral blood neutrophils (at protein level). Strongly expressed in the prostate, small intestine and colon and moderately expressed in the bone mar
Target Synonyms
Antiapoptotic protein GW112; bA209J19.1; G-CSF-stimulated clone 1 protein; GC1; GW112; hGC 1; hGC-1; hOLfD; KIAA4294; olfactomedin 4; Olfactomedin-4; OlfD; OLFM4; OLFM4_HUMAN; OLM4; UNQ362
Target Background
This gene was originally cloned from human myeloblasts and found to be selectively expressed in inflammed colonic epithelium. This gene encodes a member of the olfactomedin family. The encoded protein is an antiapoptotic factor that promotes tumor growth and is an extracellular matrix glycoprotein that facilitates cell adhesion.
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