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Rabbit anti-Human SRR Polyclonal Antibody

The antibody against SRR was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-340 of human SRR (NP_068766.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-01002A

The antibody against SRR was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-340 of human SRR (NP_068766.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-01002A ClonalityPolyclonal
Host SpeciesRabbitTarget NameSRR
Target SynonymsILV1; ISO1; SRRFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesRat brain, Mouse brain, SH-SY5Y, U-87MGApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-340 of human SRR (NP_068766.1).Target SpeciesHuman
Uniprot IDQ9GZT4Immunogen Sequence
Background Information
  • Uniprot Id

    Q9GZT4

  • Target Species

    Human

  • Target Name

    SRR

  • Target Full Name

    Serine racemase

  • Target Function

    Catalyzes the synthesis of D-serine from L-serine. D-serine is a key coagonist with glutamate at NMDA receptors. Has dehydratase activity towards both L-serine and D-serine.

  • Target Protein Families

    Serine/threonine dehydratase family

  • Target Tissue Specificity

    Brain: expressed at high levels in hippocampus and corpus callosum, intermediate levels in substantia nigra and caudate, and low levels in amygdala, thalamus, and subthalamic nuclei. Expressed in heart, skeletal muscle, kidney and liver.

  • Target Research Area

    Neuroscience

  • Target Synonyms

    D serine ammonia lyase; D serine dehydratase; D-serine ammonia-lyase; D-serine dehydratase; ILV1; ISO1; L serine ammonia lyase; L serine dehydratase; L-serine ammonia-lyase; L-serine dehydratase; Serine racemase; srr; SRR_HUMAN

  • Target Background

    Enables several functions, including L-serine ammonia-lyase activity; PDZ domain binding activity; and anion binding activity. Involved in pyruvate biosynthetic process; response to lipopolysaccharide; and serine family amino acid metabolic process. Located in cytoplasm and neuronal cell body.

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