Rabbit anti-Human CD300A Polyclonal Antibody

The antibody against CD300A was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 18-180 of human CD300A (NP_009192.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-01180A

Number

Cat.No	ADA-01180A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	CD300A
Target Synonyms	IRC1; IRC2; CLM-8; IRp60; IGSF12; CMRF35H; CMRF-35H; CMRF35-H; CMRF35H9; CMRF35-H9; IRC1/IRC2; CMRF-35-H9; CD300A	Form	Liquid
Species Reactivity	Human	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	THP-1	Application	ELISA, WB

Cat.No

ADA-01180A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

CD300A

Target Synonyms

IRC1; IRC2; CLM-8; IRp60; IGSF12; CMRF35H; CMRF-35H; CMRF35-H; CMRF35H9; CMRF35-H9; IRC1/IRC2; CMRF-35-H9; CD300A

Form

Liquid

Species Reactivity

Human

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

THP-1

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 18-180 of human CD300A (NP_009192.2).	Target Species	Human
Immunogen Sequence	LSKCRTVAGPVGGSLSVQCPYEKEHRTLNKYWCRPPQIFLCDKIVETKGSAGKRNGRVSIRDSPANLSFTVTLENLTEEDAGTYWCGVDTPWLRDFHDPVVEVEVSVFPASTSMTPASITAAKTSTITTAFPPVSSTTLFAVGATHSASIQEETEEVVNSQLP	Uniprot ID	Q9UGN4

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 18-180 of human CD300A (NP_009192.2).

Target Species

Human

Immunogen Sequence

LSKCRTVAGPVGGSLSVQCPYEKEHRTLNKYWCRPPQIFLCDKIVETKGSAGKRNGRVSIRDSPANLSFTVTLENLTEEDAGTYWCGVDTPWLRDFHDPVVEVEVSVFPASTSMTPASITAAKTSTITTAFPPVSSTTLFAVGATHSASIQEETEEVVNSQLP

Uniprot ID

Q9UGN4

Background Information

Uniprot Id

Q9UGN4
Target Species

Human
Target Name

CD300A
Target Full Name

CMRF35-like molecule 8
Target Function

Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation. Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 but not TRIF through activation of PTPN6.
Target Subcellular Location

Cell membrane; Single-pass type I membrane protein.
Target Protein Families

CD300 family
Target Tissue Specificity

Expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes.
Target Research Area

Immunology
Target Synonyms

CD300 antigen-like family member A; CD300a; CD300a antigen; CD300a molecule; CLM-8; CLM8_HUMAN; CMRF 35 H9; CMRF-35-H9; CMRF35-H; CMRF35-H9; CMRF35-like molecule 8; CMRF35H; CMRF35H leukocyte immunoglobulin like receptor; CMRF35H9; IgSF12; Immunoglobulin superfamily member 12; Inhibitory receptor protein 60; IRC1; IRC1/IRC2; IRC2; IRp60; Leukocyte membrane antigen; Mast cell derived paired immunoglobulin like receptor 1; NK inhibitory receptor; Polymeric immunoglobulin receptor 4
Target Background

This gene encodes a member of the CD300 glycoprotein family of cell surface proteins found on leukocytes involved in immune response signaling pathways. This gene is located on chromosome 17 in a cluster with all but one of the other family members. Multiple transcript variants encoding different isoforms have been found for this gene.

Rabbit anti-Human CD300A Polyclonal Antibody

Specifications

Immunogen Information

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