Rabbit anti-Human INF2 Polyclonal Antibody

The antibody against INF2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human INF2 (NP_116103.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-01203A

Number

Cat.No	ADA-01203A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	INF2
Target Synonyms	FSGS5; CMTDIE; pp9484; C14orf151; C14orf173; INF2	Form	Liquid
Species Reactivity	Human	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa, 293T, BT-474, HepG2	Application	ELISA, WB

Cat.No

ADA-01203A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

INF2

Target Synonyms

FSGS5; CMTDIE; pp9484; C14orf151; C14orf173; INF2

Form

Liquid

Species Reactivity

Human

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa, 293T, BT-474, HepG2

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human INF2 (NP_116103.1).	Target Species	Human
Immunogen Sequence	MSVKEGAQRKWAALKEKLGPQDSDPTEANLESADPELCIRLLQMPSVVNYSGLRKRLEGSDGGWMVQFLEQSGLDLLLEALARLSGRGVARISDALLQLTCVSCVRAVMNSRQGIEYILSNQGYVRQLSQALDTSNVMVKKQVFELLAALCIYSPEGHVLTLDALDHYKTVCSQQYRFSIVMNELSGSDN	Uniprot ID	Q27J81

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human INF2 (NP_116103.1).

Target Species

Human

Immunogen Sequence

MSVKEGAQRKWAALKEKLGPQDSDPTEANLESADPELCIRLLQMPSVVNYSGLRKRLEGSDGGWMVQFLEQSGLDLLLEALARLSGRGVARISDALLQLTCVSCVRAVMNSRQGIEYILSNQGYVRQLSQALDTSNVMVKKQVFELLAALCIYSPEGHVLTLDALDHYKTVCSQQYRFSIVMNELSGSDN

Uniprot ID

Q27J81

Background Information

Uniprot Id

Q27J81
Target Species

Human
Target Name

INF2
Target Full Name

Inverted formin-2
Target Function

Severs actin filaments and accelerates their polymerization and depolymerization.
Target Involvement

Focal segmental glomerulosclerosis 5 (FSGS5); Charcot-Marie-Tooth disease, dominant, intermediate type, E (CMTDIE)
Target Subcellular Location

Cytoplasm, perinuclear region.
Target Protein Families

Formin homology family
Target Tissue Specificity

Widely expressed. In the kidney, expression is apparent in podocytes and some tubule cells.
Target Synonyms

C14orf151; C14orf173; CMTDIE; DKFZp762A0214; FLJ22056; FSGS5; HBEAG binding protein 2 binding protein C; HBEBP2 binding protein C; HBEBP2-binding protein C; INF 2; inf2; INF2_HUMAN; Inverted formin 2; Inverted formin FH2 and WH2 domain containing; Inverted formin-2; MGC13251; pp9484
Target Background

This gene represents a member of the formin family of proteins. It is considered a diaphanous formin due to the presence of a diaphanous inhibitory domain located at the N-terminus of the encoded protein. Studies of a similar mouse protein indicate that the protein encoded by this locus may function in polymerization and depolymerization of actin filaments. Mutations at this locus have been associated with focal segmental glomerulosclerosis 5.

Rabbit anti-Human INF2 Polyclonal Antibody

Specifications

Immunogen Information

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