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The antibody against ATP23 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-246 of human ATP23 (NP_150592.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
The antibody against ATP23 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-246 of human ATP23 (NP_150592.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
| Cat.No | ADA-03312A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ATP23 |
| Target Synonyms | KUB3; XRCC6BP1; ATP23 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat brain, Mouse brain | Application | ELISA, WB, IF/ICC, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-246 of human ATP23 (NP_150592.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9Y6H3 | Immunogen Sequence |
Uniprot Id
Q9Y6H3
Target Species
Human
Target Name
ATP23
Target Full Name
Mitochondrial inner membrane protease ATP23 homolog
Target Synonyms
ATP23; KUB3; XRCC6BP1Mitochondrial inner membrane protease ATP23 homolog; EC 3.4.24.-; Ku70-binding protein 3; XRCC6-binding protein 1
Target Background
The protein encoded by this gene is amplified in glioblastomas and interacts with the DNA binding subunit of DNA-dependent protein kinase. This kinase is involved in double-strand break repair (DSB), and higher expression of the encoded protein increases the efficiency of DSB. In addition, comparison to orthologous proteins strongly suggests that this protein is a metalloprotease important in the biosynthesis of mitochondrial ATPase. Several transcript variants encoding different isoforms have been found for this gene.
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