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The antibody against POP1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human POP1 (NP_055844.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against POP1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human POP1 (NP_055844.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-03616A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | POP1 |
| Target Synonyms | ANXD2; POP1 | Form | Liquid |
| Species Reactivity | Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney, Mouse liver, Rat liver | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human POP1 (NP_055844.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q99575 | Immunogen Sequence |
Uniprot Id
Q99575
Target Species
Human
Target Name
POP1
Target Full Name
Ribonucleases P/MRP protein subunit POP1
Target Function
Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences.
Target Involvement
Anauxetic dysplasia 2 (ANXD2)
Target Subcellular Location
Nucleus, nucleolus.
Target Synonyms
4932434G09Rik; hPOP1; KIAA0061; MGC17365; MGC36536; POP1; POP1_HUMAN; Processing of precursor 1; Processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae); Processing of precursors 1; Ribonucleases P/MRP protein subunit homolog; Ribonucleases P/MRP protein subunit POP1
Target Background
This gene encodes the protein subunit of two different small nucleolar ribonucleoprotein complexes: the endoribonuclease for mitochondrial RNA processing complex and the ribonuclease P complex. The encoded protein is a ribonuclease that localizes to the nucleus and functions in pre-RNA processing. This protein is also an autoantigen in patients suffering from connective tissue diseases. Alternative splicing results in multiple transcript variants.
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