Rabbit anti-Human NFIB Polyclonal Antibody

The antibody against NFIB was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human NFIB (NP_005587.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

ADA-10112A

Number

Cat.No	ADA-10112A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	NFIB
Target Synonyms	CTF; MACID; NF1-B; NFI-B; NFIB2; NFIB3; NF-I/B; NFI-RED; HMGIC/NFIB; NFIB	Form	Liquid
Species Reactivity	Human, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa	Application	ELISA, WB, IHC-P

Cat.No

ADA-10112A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

NFIB

Target Synonyms

CTF; MACID; NF1-B; NFI-B; NFIB2; NFIB3; NF-I/B; NFI-RED; HMGIC/NFIB; NFIB

Form

Liquid

Species Reactivity

Human, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa

Application

ELISA, WB, IHC-P

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human NFIB (NP_005587.2).	Target Species	Human
Immunogen Sequence	SRTWHERDQDMSSPTTMKKPEKPLFSSASPQDSSPRLSTFPQHHHPGIPGVAHSVISTRTPPPPSPLPFPTQAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYVPSYDPSSPQTSQSWYLG	Uniprot ID	O00712

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human NFIB (NP_005587.2).

Target Species

Human

Immunogen Sequence

SRTWHERDQDMSSPTTMKKPEKPLFSSASPQDSSPRLSTFPQHHHPGIPGVAHSVISTRTPPPPSPLPFPTQAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYVPSYDPSSPQTSQSWYLG

Uniprot ID

O00712

Background Information

Uniprot Id

O00712
Target Species

Human
Target Name

NFIB
Target Full Name

Nuclear factor 1 B-type
Target Function

Transcriptional activator of GFAP, essential for proper brain development. Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.
Target Subcellular Location

Nucleus.
Target Protein Families

CTF/NF-I family
Target Synonyms

CCAAT Box Binding Transcription Factor; CCAAT-box-binding transcription factor; CTF; HMGIC/NFIB; NF-I/B; NF1-B; NF1B; NF1B2; NFI-B; NFI-RED; Nfib; NFIB_HUMAN; NFIB2; NFIB3; Nuclear factor 1 B-type; Nuclear factor 1/B; Nuclear Factor 1B; Nuclear Factor I B; Nuclear factor I/B; TGGCA Binding Protein; TGGCA-binding protein; TRANSCRIPTION FACTOR NFIB
Target Background

Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and transcription regulator inhibitor activity. Involved in brain development; negative regulation of DNA binding activity; and regulation of transcription by RNA polymerase II. Located in fibrillar center and nucleoplasm.

Rabbit anti-Human NFIB Polyclonal Antibody

Specifications

Immunogen Information

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