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Rabbit anti-Human COL10A1 Polyclonal Antibody

The antibody against COL10A1 was raised in Rabbit using the recombinant protein of human COL10A1 as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-10661A

The antibody against COL10A1 was raised in Rabbit using the recombinant protein of human COL10A1 as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-10661A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCOL10A1
Target SynonymsCOL10A1; collagen alpha-1(X) chainFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesHT-1080ApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant protein of human COL10A1.Target SpeciesHuman
Immunogen SequenceMPEGFIKAGQRPSLSGTPLVSANQGVTGMPVSAFTVILSKAYPAIGTPIPFDKILYNRQQHYDPRTGIFTCQIPGIYYFSYHVHVKGTHVWVGLYKNGTPVMYTYDEYTKGYLDQASGSAIIDLTENDQVWLQLPNAESNGLYSSEYVHSSFSGFLVAPMUniprot IDQ03692
Background Information
  • Uniprot Id

    Q03692

  • Target Species

    Human

  • Target Name

    COL10A1

  • Target Full Name

    Collagen alpha-1(X) chain

  • Target Function

    Type X collagen is a product of hypertrophic chondrocytes and has been localized to presumptive mineralization zones of hyaline cartilage.

  • Target Involvement

    Schmid type metaphyseal chondrodysplasia (SMCD)

  • Target Subcellular Location

    Secreted, extracellular space, extracellular matrix.

  • Target Synonyms

    COL10A1; collagen alpha-1(X) chain

  • Target Background

    This gene encodes the alpha chain of type X collagen, a short chain collagen expressed by hypertrophic chondrocytes during endochondral ossification. Unlike type VIII collagen, the other short chain collagen, type X collagen is a homotrimer. Mutations in this gene are associated with Schmid type metaphyseal chondrodysplasia (SMCD) and Japanese type spondylometaphyseal dysplasia (SMD).

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