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The antibody against ascl1a was raised in rabbit using the Recombinant Zebrafish Achaete-scute homolog 1a protein (1-196AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against ascl1a was raised in rabbit using the Recombinant Zebrafish Achaete-scute homolog 1a protein (1-196AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-10177A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ascl1a |
| Target Synonyms | ascl1a antibody; ash antibody; ash1a antibody; asha antibody; piaAchaete-scute homolog 1a antibody; Zash-1a antibody; Pituitary-absent protein antibody | Form | Liquid |
| Species Reactivity | Zebrafish | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Zebrafish Achaete-scute homolog 1a protein (1-196AA) | Target Species | Danio rerio (Zebrafish) (Brachydanio rerio) |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q90259 |
Uniprot Id
Q90259
Target Species
Zebrafish
Target Name
ASCL1A
Target Function
Transcriptional regulator. May mediate transcription activation by binding to the E box-containing promoter. Involved in neurogenesis. Required for the development of neurons in the epiphysis, acting partially redundantly with neurog1 and downstream of flh. Involved in maintaining rhombomere boundaries in the hindbrain, probably via up-regulation of delta expression. Also involved in pituitary development; required cell-autonomously in adenohypophyseal cells for endocrine differentiation and for survival of a subset of cells.
Target Subcellular Location
Nucleus.
Target Tissue Specificity
In the 24 hours embryo, expressed in the dorsal hindbrain in two bilaterally symmetrical lines of cells marking the boundary between the alar and basal plates, and ventrally in rhombomere 1 near the floor plate. Also expressed in embryonic adenohypophysis
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