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The antibody against ruvC was raised in rabbit using the Recombinant Escherichia coli Crossover junction endodeoxyribonuclease RuvC protein (2-173AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against ruvC was raised in rabbit using the Recombinant Escherichia coli Crossover junction endodeoxyribonuclease RuvC protein (2-173AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-20457A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ruvC |
| Form | Liquid | Species Reactivity | Escherichia coli |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA | Storage | Upon receipt |
| Immunogen Description | Recombinant Escherichia coli Crossover junction endodeoxyribonuclease RuvC protein (2-173AA) | Target Species | Escherichia coli (strain K12) |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P0A814 |
Uniprot Id
P0A814
Target Species
E.coli
Target Name
RUVC
Target Function
Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
Target Subcellular Location
Cytoplasm. Note=In 15% of cell localizes to discrete nucleoid foci (probable DNA damage sites) upon treatment with mitomycin C (MMC) for 2 hours.
Target Protein Families
RuvC family
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