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The antibody against NFE4 was raised in rabbit using the Synthesized peptide derived from the Human NF-E4 around the acetylation site of K43. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
The antibody against NFE4 was raised in rabbit using the Synthesized peptide derived from the Human NF-E4 around the acetylation site of K43. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
$167.00
Western Blot analysis of AD-293 cells using Acetyl-NF-E4 (K43) Polyclonal Antibody
Western Blot analysis of AD-293 cells using Acetyl-NF-E4 (K43) Polyclonal Antibody2
| Cat.No | ADC-39854A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NFE4 |
| Target Synonyms | NFE4Transcription factor NF-E4 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Human NF-E4 around the acetylation site of K43. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q86UQ8 |
Uniprot Id
Q86UQ8
Target Species
Human
Target Name
NFE4
Target Full Name
Transcription factor NF-E4
Target Function
Functions as part of the SSP (stage selector protein) complex, a complex that contributes to the preferential expression of the gamma-gene in fetal erythroid cells by facilitating the interaction of the gamma-globin genes with enhancer elements contained in the locus control region (LCR). The complex binds to the stage selector element (SSE) in the proximal gamma-globin promoter. In contrast, isoform 2 acts as a repressor of gamma-globin gene expression by preventing NFE2 and RNA polymerase II recruitment to the promoter.
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Specifically expressed in fetal liver, cord blood and bone marrow. Also expressed in the K562 and HEL cell lines, which constitutively express the fetal globin genes.
Target Synonyms
NFE4Transcription factor NF-E4
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