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Rabbit anti-Human ACTN3 Polyclonal Antibody

The antibody against ACTN3 was raised in rabbit using the Fusion protein of Human ACTN3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

ADC-31092A

The antibody against ACTN3 was raised in rabbit using the Fusion protein of Human ACTN3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

$299.00

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Specifications


Cat.No ADC-31092A ClonalityPolyclonal
Host SpeciesRabbitTarget NameACTN3
FormLiquidSpecies ReactivityHuman, Mouse
IsotypeIgGStorage Buffer0.05% NaN3, 40% Glycerol., pH7.4 PBS
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionFusion protein of Human ACTN3Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ08043
Background Information
  • Uniprot Id

    Q08043

  • Target Species

    Human

  • Target Name

    ACTN3

  • Target Full Name

    Alpha-actinin-3

  • Target Function

    F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.

  • Target Protein Families

    Alpha-actinin family

  • Target Tissue Specificity

    Expressed only in a subset of type 2 skeletal muscle fibers.

  • Target Synonyms

    ACTN3D; ACTN3

  • Target Background

    This gene encodes a member of the alpha-actin binding protein gene family. The encoded protein is primarily expressed in skeletal muscle and functions as a structural component of sarcomeric Z line. This protein is involved in crosslinking actin containing thin filaments. An allelic polymorphism in this gene results in both coding and non-coding variants; the reference genome represents the coding allele. The non-functional allele of this gene is associated with elite athlete status.

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