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The antibody against ACTR8 was raised in rabbit using the Recombinant Human Actin-related protein 8 protein (35-175AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
The antibody against ACTR8 was raised in rabbit using the Recombinant Human Actin-related protein 8 protein (35-175AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
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| Cat.No | ADC-25291A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ACTR8 |
| Target Synonyms | Actin-related protein 8 antibody; Actr8 antibody; ARP8_HUMAN antibody; hArp8 antibody; INO80 complex subunit N antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Actin-related protein 8 protein (35-175AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9H981 |
Uniprot Id
Q9H981
Target Species
Human
Target Name
ACTR8
Target Full Name
Actin-related protein 8
Target Function
Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize.; Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. Required for the recruitment of INO80 (and probably the INO80 complex) to sites of DNA damage. Strongly prefer nucleosomes and H3-H4 tetramers over H2A-H2B dimers, suggesting it may act as a nucleosome recognition module within the complex.
Target Subcellular Location
Nucleus. Chromosome. Note=Specifically localizes to mitotic chromosomes.
Target Protein Families
Actin family, ARP8 subfamily
Target Synonyms
Actin-related protein 8; Actr8; ARP8_HUMAN; hArp8; INO80 complex subunit N
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