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Rabbit anti-Human ADGRL2 Polyclonal Antibody

The antibody against ADGRL2 was raised in rabbit using the Recombinant Human Adhesion G protein-coupled receptor L2 protein (400-480AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

ADC-16344A

The antibody against ADGRL2 was raised in rabbit using the Recombinant Human Adhesion G protein-coupled receptor L2 protein (400-480AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-16344A ClonalityPolyclonal
Host SpeciesRabbitTarget NameADGRL2
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Adhesion G protein-coupled receptor L2 protein (400-480AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDO95490
Background Information
  • Uniprot Id

    O95490

  • Target Species

    Human

  • Target Name

    ADGRL2

  • Target Full Name

    Adhesion G protein-coupled receptor L2

  • Target Function

    Calcium-independent receptor of low affinity for alpha-latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis.

  • Target Subcellular Location

    Membrane; Multi-pass membrane protein.

  • Target Protein Families

    G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily

  • Target Tissue Specificity

    Expressed very widely in all normal tissues tested. Expression is variable in tumor cell lines, apparently elevated in some lines and absent or markedly reduced in others.

  • Target Synonyms

    Adgrl2; Adhesion G protein-coupled receptor L2; AGRL2_HUMAN; Calcium-independent alpha-latrotoxin receptor 2; CIRL-2; CL2; KIAA0786; Latrophilin 1; Latrophilin 2; Latrophilin homolog 1; latrophilin homolog 2; Latrophilin-2; LEC1; Lectomedin-1; LPH2; LPHH1; LPHN2_HUMAN

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