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The antibody against ADGRL4 was raised in rabbit using the Recombinant Human Adhesion G protein-coupled receptor L4 protein (85-299AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against ADGRL4 was raised in rabbit using the Recombinant Human Adhesion G protein-coupled receptor L4 protein (85-299AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
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Immunohistochemistry of paraffin-embedded human small intestine tissue using ADGRL4 Antibody at dilution of 1:1002
| Cat.No | ADC-25281A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ADGRL4 |
| Target Synonyms | ADGRL4; ELTD1; ETL; UNQ202/PRO228; Adhesion G protein-coupled receptor L4; EGF, latrophilin and seven transmembrane domain-containing protein 1; EGF-TM7-latrophilin-related protein; ETL protein | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Adhesion G protein-coupled receptor L4 protein (85-299AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9HBW9 |
Uniprot Id
Q9HBW9
Target Species
Human
Target Name
ADGRL4
Target Full Name
Adhesion G protein-coupled receptor L4
Target Function
Endothelial orphan receptor that acts as a key regulator of angiogenesis.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily
Target Tissue Specificity
Detected in the majority of epithelial cells in tumor and normal tissues. Expressed also in human umbilical vein endothelial cells.
Target Synonyms
ADGRL4; ELTD1; ETL; UNQ202/PRO228; Adhesion G protein-coupled receptor L4; EGF, latrophilin and seven transmembrane domain-containing protein 1; EGF-TM7-latrophilin-related protein; ETL protein
Target Background
Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to be located in cytoplasmic vesicle and plasma membrane. Predicted to be integral component of plasma membrane. Biomarker of glioblastoma and hypertrophic cardiomyopathy.
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