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Rabbit anti-Human ADK Polyclonal Antibody

The antibody against ADK was raised in rabbit using the Fusion protein of Human ADK as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

ADC-31043A

The antibody against ADK was raised in rabbit using the Fusion protein of Human ADK as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

$299.00

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Specifications


Cat.No ADC-31043A ClonalityPolyclonal
Host SpeciesRabbitTarget NameADK
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer0.05% NaN3, 40% Glycerol., pH7.4 PBS
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionFusion protein of Human ADKTarget SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP55263
Background Information
  • Uniprot Id

    P55263

  • Target Species

    Human

  • Target Name

    ADK

  • Target Full Name

    Adenosine kinase

  • Target Function

    ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives. Serves as a potential regulator of concentrations of extracellular adenosine and intracellular adenine nucleotides.

  • Target Involvement

    Hypermethioninemia due to adenosine kinase deficiency (HMAKD)

  • Target Subcellular Location

    [Isoform 1]: Nucleus.; [Isoform 2]: Cytoplasm.

  • Target Protein Families

    Carbohydrate kinase PfkB family

  • Target Tissue Specificity

    Widely expressed. Highest level in placenta, liver, muscle and kidney.

  • Target Synonyms

    2310026J05Rik; 5033405D03Rik; Adenosine 5''-phosphotransferase; Adenosine kinase; adk; ADK_HUMAN; AI255373; AI987814; AK; MGC6593; OTTHUMP00000019864; OTTHUMP00000019865

  • Target Background

    This gene an enzyme which catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Multiple transcript variants encoding different isoforms have been found for this gene.

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