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The antibody against ADSS was raised in rabbit using the Recombinant Human Adenylosuccinate synthetase isozyme 2 protein (1-280AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against ADSS was raised in rabbit using the Recombinant Human Adenylosuccinate synthetase isozyme 2 protein (1-280AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
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Immunohistochemistry of paraffin-embedded human colon tissue using ADSS Antibody at dilution of 1:1002
| Cat.No | ADC-44373A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ADSS |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Adenylosuccinate synthetase isozyme 2 protein (1-280AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P30520 |
Uniprot Id
P30520
Target Species
Human
Target Name
ADSS2
Target Full Name
Adenylosuccinate synthetase isozyme 2
Target Function
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
Target Subcellular Location
Cytoplasm. Mitochondrion. Note=Partially associated with particulate fractions.
Target Protein Families
Adenylosuccinate synthetase family
Target Synonyms
ADSS2; ADSS; Adenylosuccinate synthetase isozyme 2; AMPSase 2; AdSS 2; EC 6.3.4.4; Adenylosuccinate synthetase; acidic isozyme; Adenylosuccinate synthetase; liver isozyme; L-type adenylosuccinate synthetase; IMP--aspartate ligase 2
Target Background
This gene encodes the enzyme adenylosuccinate synthetase which catalyzes the first committed step in the conversion of inosine monophosphate to adenosine monophosphate. A pseudogene of this gene is found on chromosome 17.
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