Rabbit anti-Human AHSP Polyclonal Antibody

The antibody against AHSP was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-102 of human AHSP (NP_057717.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-03008A

Number

Cat.No	ADA-03008A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	AHSP
Target Synonyms	EDRF; ERAF; AHSP	Form	Liquid
Species Reactivity	Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	Mouse liver, Rat liver	Application	ELISA, WB

Cat.No

ADA-03008A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

AHSP

Target Synonyms

EDRF; ERAF; AHSP

Form

Liquid

Species Reactivity

Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

Mouse liver, Rat liver

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-102 of human AHSP (NP_057717.1).	Target Species	Human
Immunogen Sequence	MALLKANKDLISAGLKEFSVLLNQQVFNDPLVSEEDMVTVVEDWMNFYINYYRQQVTGEPQERDKALQELRQELNTLANPFLAKYRDFLKSHELPSHPPPSS	Uniprot ID	Q9NZD4

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-102 of human AHSP (NP_057717.1).

Target Species

Human

Immunogen Sequence

MALLKANKDLISAGLKEFSVLLNQQVFNDPLVSEEDMVTVVEDWMNFYINYYRQQVTGEPQERDKALQELRQELNTLANPFLAKYRDFLKSHELPSHPPPSS

Uniprot ID

Q9NZD4

Background Information

Uniprot Id

Q9NZD4
Target Species

Human
Target Name

AHSP
Target Full Name

Alpha-hemoglobin-stabilizing protein
Target Function

Acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Specifically protects free alpha-hemoglobin from precipitation. It is predicted to modulate pathological states of alpha-hemoglobin excess such as beta-thalassemia.
Target Subcellular Location

Cytoplasm.
Target Protein Families

AHSP family
Target Tissue Specificity

Expressed in blood and bone marrow.
Target Research Area

Signal Transduction
Target Synonyms

AHSP; AHSP_HUMAN; Alpha hemoglobin stabilizing protein; Alpha-hemoglobin-stabilizing protein; EDRF; ERAF; Erythroid associated factor; Erythroid differentiation associated factor; Erythroid differentiation related factor; Erythroid differentiation-related factor; Erythroid-associated factor
Target Background

This gene encodes a molecular chaperone which binds specifically to free alpha-globin and is involved in hemoglobin assembly. The encoded protein binds to monomeric alpha-globin until it has been transferred to beta-globin to form a heterodimer, which in turn binds to another heterodimer to form the stable tetrameric hemoglobin. Alternative splicing results in multiple transcript variants.

Rabbit anti-Human AHSP Polyclonal Antibody

Specifications

Immunogen Information

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