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The antibody against AIMP2 was raised in rabbit using the Recombinant Human Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 protein (141-320AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against AIMP2 was raised in rabbit using the Recombinant Human Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 protein (141-320AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
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Immunohistochemistry of paraffin-embedded human colon cancer using AIMP2 Antibody at dilution of 1:1002
| Cat.No | ADC-40241A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | AIMP2 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 protein (141-320AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q13155 |
Uniprot Id
Q13155
Target Species
Human
Target Name
AIMP2
Target Full Name
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2
Target Function
Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.
Target Subcellular Location
Cytoplasm, cytosol. Nucleus.
Target Research Area
Neuroscience
Target Synonyms
Aimp2; AIMP2_HUMAN; Aminoacyl tRNA synthase complex-interacting multifunctional protein 2; Aminoacyl tRNA synthetase complex interacting multifunctional protein 2 ; ARS interacting multi functional protein 2 ; JTV 1; JTV 1 protein; JTV1; JTV1 gene; Multisynthase complex auxiliary component p38; Multisynthetase complex auxiliary component p38; P38; PRO0992; Protein JTV 1; Protein JTV-1; tRNA SYNTHETASE COFACTOR p38
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