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The antibody against ALDH1L1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human ALDH1L1 (NP_036322.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against ALDH1L1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human ALDH1L1 (NP_036322.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-11057A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ALDH1L1 |
| Target Synonyms | FDH; FTHFD; 10-fTHF; 10-FTHFDH; ALDH1L1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney, Rat brain, MCF7, Mouse brain | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human ALDH1L1 (NP_036322.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | O75891 | Immunogen Sequence |
Uniprot Id
O75891
Target Species
Human
Target Name
ALDH1L1
Target Full Name
Cytosolic 10-formyltetrahydrofolate dehydrogenase
Target Subcellular Location
Cytoplasm.
Target Protein Families
GART family; Aldehyde dehydrogenase family, ALDH1L subfamily
Target Tissue Specificity
Highly expressed in liver, pancreas and kidney.
Target Synonyms
10 formyltetrahydrofolate dehydrogenase; 10 FTHFDH; 10-formyltetrahydrofolate dehydrogenase; 10-FTHFDH; AL1L1_HUMAN; Aldehyde dehydrogenase 1 family member L1; Aldehyde dehydrogenase family 1 member L1; aldh1l1; Cytosolic 10-formyltetrahydrofolate dehydrogenase; DKFZp781N0997; EC 1.5.1.6; FDH; formyltetrahydrofolate dehydrogenase; FTHFD; OTTHUMP00000155221; OTTHUMP00000214696; OTTHUMP00000214700; OTTHUMP00000222724
Target Background
The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants.
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