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Rabbit anti-Human AMBP Polyclonal Antibody

The antibody against AMBP was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 20-202 of human AMBP (NP_001624.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-04483A

The antibody against AMBP was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 20-202 of human AMBP (NP_001624.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-04483A ClonalityPolyclonal
Host SpeciesRabbitTarget NameAMBP
Target SynonymsA1M; HCP; ITI; UTI; EDC1; HI30; ITIL; IATIL; ITILC; AMBPFormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.05% proclin300, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse pancreasApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 20-202 of human AMBP (NP_001624.1).Target SpeciesHuman
Immunogen SequenceGPVPTPPDNIQVQENFNISRIYGKWYNLAIGSTCPWLKKIMDRMTVSTLVLGEGATEAEISMTSTRWRKGVCEETSGAYEKTDTDGKFLYHKSKWNITMESYVVHTNYDEYAIFLTKKFSRHHGPTITAKLYGRAPQLRETLLQDFRVVAQGVGIPEDSIFTMADRGECVPGEQEPEPILIPRUniprot IDP02760
Background Information
  • Uniprot Id

    P02760

  • Target Species

    Human

  • Target Name

    AMBP

  • Target Full Name

    Protein AMBP

  • Target Function

    Inter-alpha-trypsin inhibitor inhibits trypsin, plasmin, and lysosomal granulocytic elastase. Inhibits calcium oxalate crystallization.; Trypstatin is a trypsin inhibitor.

  • Target Subcellular Location

    Secreted.

  • Target Protein Families

    Calycin superfamily, Lipocalin family

  • Target Tissue Specificity

    Expressed by the liver and secreted in plasma. Alpha-1-microglobulin occurs in many physiological fluids including plasma, urine, and cerebrospinal fluid. Inter-alpha-trypsin inhibitor is present in plasma and urine.

  • Target Synonyms

    A1M; HCP; ITI; UTI; EDC1; HI30; ITIL; IATIL; ITILC; AMBP

  • Target Background

    This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes.

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