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The antibody against AMPD3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human AMPD3 (NP_000471.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against AMPD3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human AMPD3 (NP_000471.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-03071A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | AMPD3 |
| Target Synonyms | AMPD3 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | NIH/3T3, RAW264.7 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human AMPD3 (NP_000471.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q01432 | Immunogen Sequence |
Uniprot Id
Q01432
Target Species
Human
Target Name
AMPD3
Target Full Name
AMP deaminase 3
Target Function
AMP deaminase plays a critical role in energy metabolism.
Target Involvement
Adenosine monophosphate deaminase deficiency erythrocyte type (AMPDDE)
Target Protein Families
Metallo-dependent hydrolases superfamily, Adenosine and AMP deaminases family
Target Synonyms
AMPD3
Target Background
This gene encodes a member of the AMP deaminase gene family. The encoded protein is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. This gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. Mutations in this gene lead to the clinically asymptomatic, autosomal recessive condition erythrocyte AMP deaminase deficiency. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.
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