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The antibody against AP3M2 was raised in rabbit using the Recombinant Human AP-3 complex subunit mu-2 protein (1-273AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against AP3M2 was raised in rabbit using the Recombinant Human AP-3 complex subunit mu-2 protein (1-273AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human adrenal gland tissue using AP3M2 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human colon cancer using AP3M2 Antibody at dilution of 1:1002
| Cat.No | ADC-22228A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | AP3M2 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human AP-3 complex subunit mu-2 protein (1-273AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P53677 |
Uniprot Id
P53677
Target Species
Human
Target Name
AP3M2
Target Full Name
AP-3 complex subunit mu-2
Target Function
Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
Target Subcellular Location
Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side.
Target Protein Families
Adaptor complexes medium subunit family
Target Synonyms
AP3M2; AP-3 complex subunit mu-2; Adaptor-related protein complex 3 subunit mu-2; Clathrin assembly protein assembly protein complex 3 mu-2 medium chain; Clathrin coat assembly protein AP47 homolog 2; Clathrin coat-associated protein AP47 homolog 2; Golgi adaptor AP-1 47 kDa protein homolog 2; HA1 47 kDa subunit homolog 2; Mu3B-adaptin; P47B
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