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The antibody against APCDD1 was raised in rabbit using the Recombinant Human Protein APCDD1 protein (22-288AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against APCDD1 was raised in rabbit using the Recombinant Human Protein APCDD1 protein (22-288AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$299.00
Western Blot | Positive WB detected in: 293T whole cell lysate, MCF-7 whole cell lysate, 293 whole cell lysate, HepG2 whole cell lysate, PC-3 whole cell lysate, Hela whole cell lysate, K562 whole cell lysate | All lanes: APCDD1 antibody at 1:1000 | Secondary | Goat polyclonal to rabbit IgG at 1/50000 dilution | Predicted band size: 59 kDa | Observed band size: 59 kDa
| Cat.No | ADC-01193A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | APCDD1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Protein APCDD1 protein (22-288AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8J025 |
Uniprot Id
Q8J025
Target Species
Human
Target Name
APCDD1
Target Full Name
Protein APCDD1
Target Function
Negative regulator of the Wnt signaling pathway. Inhibits Wnt signaling in a cell-autonomous manner and functions upstream of beta-catenin. May act via its interaction with Wnt and LRP proteins. May play a role in colorectal tumorigenesis.
Target Involvement
Hypotrichosis 1 (HYPT1)
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Target Protein Families
APCDD1 family
Target Tissue Specificity
Abundantly expressed in heart, pancreas, prostate and ovary. Moderately expressed in lung, liver, kidney, spleen, thymus, colon and peripheral lymphocytes. Abundantly expressed in both the epidermal and dermal compartments of the hair follicle. Present in
Target Synonyms
Adenomatosis polyposis coli down regulated 1; Adenomatosis polyposis coli down regulated 1 protein; Adenomatosis polyposis coli down-regulated 1 protein; APCD1_HUMAN; APCDD 1; APCDD1; B7323; DRAPC1; FP7019; HHS; HTS; hypoptrichosis simplex; Protein APCDD1
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