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The antibody against ARHGAP18 was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human ARHGAP18. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
The antibody against ARHGAP18 was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human ARHGAP18. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
$167.00
Western Blot analysis of Jurkat cells using ARHGAP18 Polyclonal Antibody
Western Blot analysis of NIH-3T3 cells using ARHGAP18 Polyclonal Antibody2
| Cat.No | ADC-39297A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ARHGAP18 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the C-terminal region of Human ARHGAP18. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8N392 |
Uniprot Id
Q8N392
Target Species
Human
Target Name
ARHGAP18
Target Full Name
Rho GTPase-activating protein 18
Target Function
Rho GTPase activating protein that suppresses F-actin polymerization by inhibiting Rho. Rho GTPase activating proteins act by converting Rho-type GTPases to an inactive GDP-bound state. Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation. Acts downstream of YAP1 and inhibits actin polymerization, which in turn reduces nuclear localization of YAP1. Regulates cell shape, spreading, and migration.
Target Subcellular Location
Cytoplasm.
Target Synonyms
4833419J07Rik; AI314906; AI843501; Arhgap18; bA307O14.2; FLJ25728; MacGAP; MGC126757; MGC138145; OTTHUMP00000017190; OTTMUSP00000028606; RHG18_HUMAN; Rho GTPase-activating protein 18; Rho-type GTPase-activating protein 18; SENEX
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