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The antibody against ARMC10 was raised in rabbit using the Human ARMC10 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against ARMC10 was raised in rabbit using the Human ARMC10 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$600.00
| Cat.No | ADC-49202A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ARMC10 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Human ARMC10 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8N2F6 |
Uniprot Id
Q8N2F6
Target Species
Human
Target Name
ARMC10
Target Full Name
Armadillo repeat-containing protein 10
Target Function
May play a role in cell survival and cell growth. May suppress the transcriptional activity of p53/TP53.
Target Subcellular Location
Endoplasmic reticulum membrane; Single-pass membrane protein.
Target Tissue Specificity
Expressed in all tissues tested with higher expression in placenta, liver, kidney, heart and brain.
Target Synonyms
ARM10_HUMAN; Armadillo repeat containing 10; Armadillo repeat containing protein 10; Armadillo repeat-containing protein 10; ARMC 10; ARMC10; FLJ37850; MGC3195; PNAS112; Specific splicing variant involved in hepatocarcinogenesis; Splicing variant involved in hepatocarcinogenesis protein; SVH
Target Background
This gene encodes a protein that contains an armadillo repeat and transmembrane domain. The encoded protein decreases the transcriptional activity of the tumor suppressor protein p53 through direct interaction with the DNA-binding domain of p53, and may play a role in cell growth and survival. Upregulation of this gene may play a role in hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3.
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