Rabbit anti-Human ARSE Polyclonal Antibody

The antibody against ARSE was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 520-589 of human ARSE (NP_000038.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-00585A

Number

Cat.No	ADA-00585A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	ARSE
Target Synonyms	ASE; ARSE; CDPX; CDPX1; CDPXR	Form	Liquid
Species Reactivity	Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	Mouse liver, Rat liver	Application	ELISA, WB

Cat.No

ADA-00585A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

ARSE

Target Synonyms

ASE; ARSE; CDPX; CDPX1; CDPXR

Form

Liquid

Species Reactivity

Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

Mouse liver, Rat liver

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 520-589 of human ARSE (NP_000038.2).	Target Species	Human
Immunogen Sequence	PSETHILTPASEPVFYQVMERVQQAVWEHQRTLSPVPLQLDRLGNIWRPWLQPCCGPFPLCWCLREDDPQ	Uniprot ID	P51690

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 520-589 of human ARSE (NP_000038.2).

Target Species

Human

Immunogen Sequence

PSETHILTPASEPVFYQVMERVQQAVWEHQRTLSPVPLQLDRLGNIWRPWLQPCCGPFPLCWCLREDDPQ

Uniprot ID

P51690

Background Information

Uniprot Id

P51690
Target Species

Human
Target Name

ARSL
Target Full Name

Arylsulfatase L
Target Function

Exhibits arylsulfatase activity towards the artifical substrate 4-methylumbelliferyl sulfate. May be essential for the correct composition of cartilage and bone matrix during development. Has no activity toward steroid sulfates.
Target Involvement

Chondrodysplasia punctata 1, X-linked recessive (CDPX1)
Target Subcellular Location

Golgi apparatus, Golgi stack.
Target Protein Families

Sulfatase family
Target Tissue Specificity

Expressed in the pancreas, liver and kidney.
Target Synonyms

ARSL; ARSE; Arylsulfatase L; EC 3.1.6.-; Arylsulfatase E; ASE
Target Background

Arylsulfatase E is a member of the sulfatase family. It is glycosylated postranslationally and localized to the golgi apparatus. Sulfatases are essential for the correct composition of bone and cartilage matrix. X-linked chondrodysplasia punctata, a disease characterized by abnormalities in cartilage and bone development, has been linked to mutations in this gene. Alternative splicing results in multiple transcript variants. A pseudogene related to this gene is located on the Y chromosome.

Rabbit anti-Human ARSE Polyclonal Antibody

Specifications

Immunogen Information

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