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The antibody against ARSE was raised in rabbit using the Synthesized peptide derived from Internal of Human ARSE. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
The antibody against ARSE was raised in rabbit using the Synthesized peptide derived from Internal of Human ARSE. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
$297.00
Western blot analysis of extracts from K562/293/Jurkat cells, using ARSE antibody.
| Cat.No | ADC-41466A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ARSE |
| Target Synonyms | ARSL antibody; ARSE antibody; Arylsulfatase L antibody; EC 3.1.6.- antibody; Arylsulfatase E antibody; ASE antibody | Form | Liquid |
| Species Reactivity | Human | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from Internal of Human ARSE. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P51690 |
Uniprot Id
P51690
Target Species
Human
Target Name
ARSL
Target Full Name
Arylsulfatase L
Target Function
Exhibits arylsulfatase activity towards the artifical substrate 4-methylumbelliferyl sulfate. May be essential for the correct composition of cartilage and bone matrix during development. Has no activity toward steroid sulfates.
Target Involvement
Chondrodysplasia punctata 1, X-linked recessive (CDPX1)
Target Subcellular Location
Golgi apparatus, Golgi stack.
Target Protein Families
Sulfatase family
Target Tissue Specificity
Expressed in the pancreas, liver and kidney.
Target Synonyms
ARSL; ARSE; Arylsulfatase L; EC 3.1.6.-; Arylsulfatase E; ASE
Target Background
Arylsulfatase E is a member of the sulfatase family. It is glycosylated postranslationally and localized to the golgi apparatus. Sulfatases are essential for the correct composition of bone and cartilage matrix. X-linked chondrodysplasia punctata, a disease characterized by abnormalities in cartilage and bone development, has been linked to mutations in this gene. Alternative splicing results in multiple transcript variants. A pseudogene related to this gene is located on the Y chromosome.
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