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The antibody against ASPM was raised in rabbit using the Recombinant Human Abnormal spindle-like microcephaly-associated protein (101-234AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against ASPM was raised in rabbit using the Recombinant Human Abnormal spindle-like microcephaly-associated protein (101-234AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using ASPM Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human lung tissue using ASPM Antibody at dilution of 1:1002
Immunofluorescent analysis of Hela cells using ASPM Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)3
| Cat.No | ADC-09051A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ASPM |
| Target Synonyms | ASPM antibody; MCPH5 antibody; Abnormal spindle-like microcephaly-associated protein antibody; Abnormal spindle protein homolog antibody; Asp homolog antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Abnormal spindle-like microcephaly-associated protein (101-234AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8IZT6 |
Uniprot Id
Q8IZT6
Target Species
Human
Target Name
ASPM
Target Full Name
Abnormal spindle-like microcephaly-associated protein
Target Function
Involved in mitotic spindle regulation and coordination of mitotic processes. The function in regulating microtubule dynamics at spindle poles including spindle orientation, astral microtubule density and poleward microtubule flux seems to depend on the association with the katanin complex formed by KATNA1 and KATNB1. Enhances the microtubule lattice severing activity of KATNA1 by recruiting the katanin complex to microtubules. Can block microtubule minus-end growth and reversely this function can be enhanced by the katanin complex. May have a preferential role in regulating neurogenesis.
Target Involvement
Microcephaly 5, primary, autosomal recessive (MCPH5)
Target Subcellular Location
Cytoplasm. Cytoplasm, cytoskeleton, spindle. Nucleus.
Target Synonyms
ASPM; MCPH5; Abnormal spindle-like microcephaly-associated protein; Abnormal spindle protein homolog; Asp homolog
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