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The antibody against ASTN2 was raised in rabbit using the Recombinant Human Astrotactin-2 protein (108-272AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against ASTN2 was raised in rabbit using the Recombinant Human Astrotactin-2 protein (108-272AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
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Immunohistochemistry of paraffin-embedded human thyroid tissue using ASTN2 Antibody at dilution of 1:1002
| Cat.No | ADC-12856A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ASTN2 |
| Target Synonyms | Astn2 antibody; ASTN2_HUMAN antibody; Astrotactin 2 antibody; Astrotactin-2 antibody; bA264C15.1 antibody; bA67K19.1 antibody; KIAA0634 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Astrotactin-2 protein (108-272AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O75129 |
Uniprot Id
O75129
Target Species
Human
Target Name
ASTN2
Target Full Name
Astrotactin-2
Target Function
Mediates recycling of the neuronal cell adhesion molecule ASTN1 to the anterior pole of the cell membrane in migrating neurons. Promotes ASTN1 internalization and intracellular transport of endocytosed ASTN1. Selectively binds inositol-4,5-bisphosphate, inositol-3,4,5-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, suggesting it is recruited to membranes that contain lipids with a phosphoinositide headgroup (Ref.6).
Target Subcellular Location
Membrane; Multi-pass membrane protein. Perikaryon. Cytoplasm, cell cortex. Early endosome. Late endosome. Cytoplasmic vesicle, clathrin-coated vesicle. Cytoplasmic vesicle.
Target Protein Families
Astrotactin family
Target Synonyms
Astn2; ASTN2_HUMAN; Astrotactin 2; Astrotactin-2; bA264C15.1; bA67K19.1; KIAA0634
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