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Rabbit anti-Human ATOH7 Polyclonal Antibody

The antibody against ATOH7 was raised in rabbit using the Recombinant Human Protein atonal homolog 7 protein (47-152AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

ADC-17183A

The antibody against ATOH7 was raised in rabbit using the Recombinant Human Protein atonal homolog 7 protein (47-152AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-17183A ClonalityPolyclonal
Host SpeciesRabbitTarget NameATOH7
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Protein atonal homolog 7 protein (47-152AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ8N100
Background Information
  • Uniprot Id

    Q8N100

  • Target Species

    Human

  • Target Name

    ATOH7

  • Target Full Name

    Transcription factor ATOH7

  • Target Function

    Transcription factor that positively regulates the determination of retinal ganglion cell fate and formation of the optic nerve and retino-hypothalamic tract. Required for retinal circadian rhythm photoentrainment.

  • Target Involvement

    Persistent hyperplastic primary vitreous, autosomal recessive (PHPVAR)

  • Target Subcellular Location

    Nucleus.

  • Target Synonyms

    ATOH7; ATOH7_HUMAN; Atonal homolog 7 (Drosophila); Atonal Homolog 7; bHLHa13; Class A basic helix-loop-helix protein 13; hATH5; Helix-loop-helix protein hATH-5; Math5; Protein atonal homolog 7

  • Target Background

    This intronless gene encodes a member of the basic helix-loop-helix family of transcription factors, with similarity to Drosophila atonal gene that controls photoreceptor development. Studies in mice suggest that this gene plays a central role in retinal ganglion cell and optic nerve formation. Mutations in this gene are associated with nonsyndromic congenital retinal nonattachment.

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