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The antibody against ATP2B3 was raised in rabbit using the Recombinant Human Plasma membrane calcium-transporting ATPase 3 protein (1057-1220AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.
The antibody against ATP2B3 was raised in rabbit using the Recombinant Human Plasma membrane calcium-transporting ATPase 3 protein (1057-1220AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.
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Western Blot | Positive WB detected in: Jurkat whole cell lysate | All lanes: ATP2B3 antibody at 1:500 | Secondary | Goat polyclonal to rabbit IgG at 1/50000 dilution | Predicted band size: 135, 129, 128, 133, 127, 125, 123 kDa | Observed band size: 135 kDa
| Cat.No | ADC-02093A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ATP2B3 |
| Target Synonyms | ATP2B3Plasma membrane calcium-transporting ATPase 3 antibody; PMCA3 antibody; EC 7.2.2.10 antibody; Plasma membrane calcium ATPase isoform 3 antibody; Plasma membrane calcium pump isoform 3 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Plasma membrane calcium-transporting ATPase 3 protein (1057-1220AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q16720 |
Uniprot Id
Q16720
Target Species
Human
Target Name
ATP2B3
Target Full Name
Plasma membrane calcium-transporting ATPase 3
Target Function
ATP-driven Ca(2+) ion pump involved in the maintenance of basal intracellular Ca(2+) levels at the presynaptic terminals. Uses ATP as an energy source to transport cytosolic Ca(2+) ions across the plasma membrane to the extracellular compartment. May counter-transport protons, but the mechanism and the stoichiometry of this Ca(2+)/H(+) exchange remains to be established.
Target Involvement
Spinocerebellar ataxia, X-linked 1 (SCAX1)
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Cell junction, synapse, presynaptic cell membrane; Multi-pass membrane protein.
Target Protein Families
Cation transport ATPase (P-type) (TC 3.A.3) family, Type IIB subfamily
Target Tissue Specificity
Highly expressed in the cerebellum. Expressed in adrenal glands.
Target Synonyms
ATP2B3Plasma membrane calcium-transporting ATPase 3; PMCA3; EC 7.2.2.10; Plasma membrane calcium ATPase isoform 3; Plasma membrane calcium pump isoform 3
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