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The antibody against ATP9A was raised in rabbit using the Recombinant Human Probable phospholipid-transporting ATPase IIA protein (2-69AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against ATP9A was raised in rabbit using the Recombinant Human Probable phospholipid-transporting ATPase IIA protein (2-69AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry of paraffin-embedded human brain tissue using ATP9A Antibody at dilution of 1:100
| Cat.No | ADC-11276A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ATP9A |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Probable phospholipid-transporting ATPase IIA protein (2-69AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O75110 |
Uniprot Id
O75110
Target Species
Human
Target Name
ATP9A
Target Full Name
Probable phospholipid-transporting ATPase IIA
Target Function
Plays a role in regulating membrane trafficking of cargo proteins, namely endosome to plasma membrane recycling and endosome to trans-Golgi network retrograde transport. In complex with MON2 and DOP1B, regulates SNX3 retromer-mediated endosomal sorting of WLS, a transporter of Wnt morphogens in developing tissues. Participates in the formation of endosomal carriers that direct WLS trafficking back to Golgi, away from lysosomal degradation. Appears to be implicated in intercellular communication by negatively regulating the release of exosomes. The flippase activity towards membrane lipids and its role in membrane asymmetry remains to be proved.
Target Subcellular Location
Early endosome membrane; Multi-pass membrane protein. Recycling endosome membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Target Protein Families
Cation transport ATPase (P-type) (TC 3.A.3) family, Type IV subfamily
Target Synonyms
ATP 9A; Atp9a; ATP9A_HUMAN; ATPase class II type 9A; ATPase IIA; ATPase type IV phospholipid transporting (P type); ATPase type IV phospholipid transporting (P type)(putative); ATPIIA; KIAA0611; Phospholipid transporting ATPase IIA; Probable phospholipid transporting ATPase IIA; Probable phospholipid-transporting ATPase IIA
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