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The antibody against BCL7B was raised in rabbit using the Human BCL7B as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against BCL7B was raised in rabbit using the Human BCL7B as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$600.00
| Cat.No | ADC-53999A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | BCL7B |
| Target Synonyms | B cell CLL/lymphoma 7 protein family member B antibody; B cell CLL/lymphoma 7B antibody; B-cell CLL/lymphoma 7 protein family member B antibody; BCL 7B antibody; BCL7B antibody; BCL7B_HUMAN antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Human BCL7B | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9BQE9 |
Uniprot Id
Q9BQE9
Target Species
Human
Target Name
BCL7B
Target Full Name
B-cell CLL/lymphoma 7 protein family member B
Target Function
Positive regulator of apoptosis. Plays a role in the Wnt signaling pathway, negatively regulating the expression of Wnt signaling components CTNNB1 and HMGA1. Involved in cell cycle progression, maintenance of the nuclear structure and stem cell differentiation. May play a role in lung tumor development or progression.
Target Involvement
BCL7B is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of BCL7B may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease.
Target Protein Families
BCL7 family
Target Tissue Specificity
Ubiquitous.
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