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The antibody against BIK was raised in rabbit using the Peptide sequence around phosphorylation site of threonine 33 (G-M-T(p)-D-S) derived from Human BIK. as the immunogen. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi This antibody has been validated on ELISA, WB, IHC.
The antibody against BIK was raised in rabbit using the Peptide sequence around phosphorylation site of threonine 33 (G-M-T(p)-D-S) derived from Human BIK. as the immunogen. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi This antibody has been validated on ELISA, WB, IHC.
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Western blot analysis of extracts from K562 cells, using BIK (Phospho-Thr33) antibody. The lane on the right is treated with the synthesized peptide.
Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue, using BIK (Phospho-Thr33) antibody. The picture on the right is treated with the synthesized peptide.2
| Cat.No | ADC-40584A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | BIK |
| Target Synonyms | BIK; NBK; Bcl-2-interacting killer; Apoptosis inducer NBK; BIP1; BP4 | Form | Liquid |
| Species Reactivity | Human | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Peptide sequence around phosphorylation site of threonine 33 (G-M-T(p)-D-S) derived from Human BIK. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q13323 |
Uniprot Id
Q13323
Target Species
Human
Target Name
BIK
Target Full Name
Bcl-2-interacting killer
Target Function
Accelerates programmed cell death. Association to the apoptosis repressors Bcl-X(L), BHRF1, Bcl-2 or its adenovirus homolog E1B 19k protein suppresses this death-promoting activity. Does not interact with BAX.
Target Subcellular Location
Endomembrane system; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein. Note=Around the nuclear envelope, and in cytoplasmic membranes.
Target Synonyms
BIK; NBK; Bcl-2-interacting killer; Apoptosis inducer NBK; BIP1; BP4
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