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The antibody against C1R was raised in rabbit using the Recombinant Human Complement C1r subcomponent protein (65-192AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against C1R was raised in rabbit using the Recombinant Human Complement C1r subcomponent protein (65-192AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
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Immunohistochemistry of paraffin-embedded human pancreatic cancer using C1R Antibody at dilution of 1:1002
| Cat.No | ADC-09762A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | C1R |
| Form | Liquid | Species Reactivity | Human, Rat |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Complement C1r subcomponent protein (65-192AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P00736 |
Uniprot Id
P00736
Target Species
Human
Target Name
C1R
Target Full Name
Complement C1r subcomponent
Target Function
C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system.
Target Involvement
Ehlers-Danlos syndrome, periodontal type, 1 (EDSPD1)
Target Subcellular Location
Secreted.
Target Protein Families
Peptidase S1 family
Target Synonyms
C1 R; C1R; C1R_HUMAN; Complement C1r; Complement C1r subcomponent; Complement C1r subcomponent light chain; Complement C1r subcomponent precursor; Complement component 1 r subcomponent; Complement component 1 subcomponent r
Target Background
This gene encodes a member of the peptidase S1 protein family. The encoded protein is a proteolytic subunit in the complement system C1 complex. The complement system acts as a mediator in the innate immune response by ultimately triggering phagocytosis, inflammation, and rupturing the bacterial cell wall. Mutations in this gene are associated with Ehlers-Danlos Syndrome.
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