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The antibody against CCDC36 was raised in rabbit using the Recombinant Human Interactor of HORMAD1 protein 1 protein (11-592AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against CCDC36 was raised in rabbit using the Recombinant Human Interactor of HORMAD1 protein 1 protein (11-592AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human lung cancer using CCDC36 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human testis tissue using CCDC36 Antibody at dilution of 1:1002
| Cat.No | ADC-44508A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CCDC36 |
| Target Synonyms | CCDC36 antibody; IHO1Interactor of HORMAD1 protein 1 antibody; Cancer/testis antigen 74 antibody; CT74 antibody; Coiled-coil domain-containing protein 36 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Interactor of HORMAD1 protein 1 protein (11-592AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8IYA8 |
Uniprot Id
Q8IYA8
Target Species
Human
Target Name
IHO1
Target Full Name
Interactor of HORMAD1 protein 1
Target Function
Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis. Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment to unsynapsed axes, meiotic silencing of unsynapsed chromatin (MSUC) or meiotic surveillance.
Target Subcellular Location
Chromosome.
Target Research Area
Cell Biology
Target Synonyms
CCDC36; IHO1Interactor of HORMAD1 protein 1; Cancer/testis antigen 74; CT74; Coiled-coil domain-containing protein 36
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