Rabbit anti-Human CD163L1 Polyclonal Antibody

Uniprot Id

Q9NR16

Target Species

Human

Target Name

CD163L1

Target Full Name

Scavenger receptor cysteine-rich type 1 protein M160

Target Subcellular Location

[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Cell membrane; Single-pass type I membrane protein.; [Isoform 3]: Secreted.

Target Tissue Specificity

Isoform 1 is highly expressed in the spleen, lymph nodes, thymus, and fetal liver and weakly expressed in bone marrow and no expression was found in peripheral blood leukocytes. Isoform 1 expression is restricted to the monocyte and macrophage cell lines.

Target Research Area

Cell Biology

Target Synonyms

B430307C05; C163B_HUMAN; CD163 antigen B; CD163 antigen-like 1; CD163 molecule-like 1; CD163b; CD163b antigen; CD163L1; CD164L1; E430002D04Rik; M160; RGD1307378; Scart1; Scavenger receptor cysteine-rich type 1 protein M160

Target Background

This gene encodes a member of the scavenger receptor cysteine-rich (SRCR) superfamily. Members of this family are secreted or membrane-anchored proteins mainly found in cells associated with the immune system. The SRCR family is defined by a 100-110 amino acid SRCR domain, which may mediate protein-protein interaction and ligand binding. The encoded protein contains twelve SRCR domains, a transmembrane region and a cytoplasmic domain. Alternative splicing results in multiple transcript variants encoding different isoforms.