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The antibody against CD99 was raised in rabbit using the Recombinant protein of Human CD99 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against CD99 was raised in rabbit using the Recombinant protein of Human CD99 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Affinity purified. This antibody has been validated on ELISA, WB, IHC.
$398.00
Western blot analysis of extracts of various cell lines, using CD99 antibody.
| Cat.No | ADC-46244A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CD99 |
| Target Synonyms | CD99; MIC2; MIC2X; MIC2Y; CD99 antigen; 12E7; E2 antigen; Protein MIC2; T-cell surface glycoprotein E2; CD antigen CD99 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant protein of Human CD99 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P14209 |
Uniprot Id
P14209
Target Species
Human
Target Name
CD99
Target Full Name
CD99 antigen
Target Function
Involved in T-cell adhesion processes and in spontaneous rosette formation with erythrocytes. Plays a role in a late step of leukocyte extravasation helping leukocytes to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PECAM1. Involved in T-cell adhesion processes.
Target Subcellular Location
Membrane; Single-pass type I membrane protein.
Target Protein Families
CD99 family
Target Synonyms
CD99; MIC2; MIC2X; MIC2Y; CD99 antigen; 12E7; E2 antigen; Protein MIC2; T-cell surface glycoprotein E2; CD antigen CD99
Target Background
The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. There is a related pseudogene located immediately adjacent to this locus.
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