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The antibody against CEP89 was raised in rabbit using the Recombinant Human Centrosomal protein of 89 kDa protein (25-235AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against CEP89 was raised in rabbit using the Recombinant Human Centrosomal protein of 89 kDa protein (25-235AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
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| Cat.No | ADC-11687A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CEP89 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Centrosomal protein of 89 kDa protein (25-235AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96ST8 |
Uniprot Id
Q96ST8
Target Species
Human
Target Name
CEP89
Target Full Name
Centrosomal protein of 89 kDa
Target Function
Required for ciliogenesis. Also plays a role in mitochondrial metabolism where it may modulate complex IV activity.
Target Involvement
Homozygous deletion comprising CEP89 and SLC7A9 genes has been reported in a patient with isolated complex IV deficiency, intellectual disability and multisystemic problems that include cystinuria, cataract, broad based walking pattern and deafness.
Target Subcellular Location
Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Mitochondrion intermembrane space. Note=Localizes to the distal appendage region of the centriole, which anchors the mother centriole to the plasma membrane.
Target Synonyms
CCDC123; Centrosomal protein 89 kDa; Centrosomal protein of 89 kDa; cep89; CEP89_HUMAN; Coiled-coil domain-containing protein 123; Coiled-coil domain-containing protein 123; mitochondrial; FLJ14640
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