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Rabbit anti-Human CLCNKB Polyclonal Antibody

The antibody against CLCNKB was raised in rabbit using the Recombinant Human Chloride channel protein ClC-Kb protein (538-687AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.

ADC-06124A

The antibody against CLCNKB was raised in rabbit using the Recombinant Human Chloride channel protein ClC-Kb protein (538-687AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.

$299.00

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Specifications


Cat.No ADC-06124A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCLCNKB
FormLiquidSpecies ReactivityHuman, Rat
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, IF, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Chloride channel protein ClC-Kb protein (538-687AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP51801
Background Information
  • Uniprot Id

    P51801

  • Target Species

    Human

  • Target Name

    CLCNKB

  • Target Full Name

    Chloride channel protein ClC-Kb

  • Target Function

    Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport. May be important in urinary concentrating mechanisms.

  • Target Involvement

    Bartter syndrome 3 (BARTS3); Bartter syndrome 4B, neonatal, with sensorineural deafness (BARTS4B)

  • Target Subcellular Location

    Cell membrane; Multi-pass membrane protein.

  • Target Protein Families

    Chloride channel (TC 2.A.49) family, CLCNKB subfamily

  • Target Tissue Specificity

    Expressed predominantly in the kidney.

  • Target Synonyms

    Bartter syndrome type 3; Chloride channel Kb; Chloride channel kidney B; Chloride channel protein ClC-Kb; Chloride channel voltage sensitive Kb; ClC K2; ClC-K2; ClCK2; CLCKB; CLCKB_HUMAN; CLCNKB; hClC Kb; hClCKb; MGC24087; OTTHUMP00000011120; OTTHUMP00000011121; RP11 5P18.8

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