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The antibody against CLYBL was raised in rabbit using the Recombinant Human Citrate lyase subunit beta-like protein, mitochondrial protein as the immunogen. This antibody exists as a non-conjugated isotype IgG, Affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against CLYBL was raised in rabbit using the Recombinant Human Citrate lyase subunit beta-like protein, mitochondrial protein as the immunogen. This antibody exists as a non-conjugated isotype IgG, Affinity purified. This antibody has been validated on ELISA, WB, IHC.
$299.00
| Cat.No | ADC-18661A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CLYBL |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | Affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Citrate lyase subunit beta-like protein, mitochondrial protein | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8N0X4 |
Uniprot Id
Q8N0X4
Target Species
Human
Target Name
CLYBL
Target Full Name
Citramalyl-CoA lyase, mitochondrial
Target Function
Mitochondrial citramalyl-CoA lyase indirectly involved in the vitamin B12 metabolism. Converts citramalyl-CoA into acetyl-CoA and pyruvate in the C5-dicarboxylate catabolism pathway. The C5-dicarboxylate catabolism pathway is required to detoxify itaconate, a vitamin B12-poisoning metabolite. Also acts as a malate synthase in vitro, converting glyoxylate and acetyl-CoA to malate. Also displays malyl-CoA thioesterase activity. Also acts as a beta-methylmalate synthase in vitro, by mediating conversion of glyoxylate and propionyl-CoA to beta-methylmalate. Also has very weak citramalate synthase activity in vitro.
Target Subcellular Location
Mitochondrion.
Target Protein Families
HpcH/HpaI aldolase family, Citrate lyase beta subunit-like subfamily
Target Synonyms
CLYBL; CLB; Citramalyl-CoA lyase; mitochondrial; EC 4.1.3.25;; 3S)-malyl-CoA thioesterase; EC 3.1.2.30; Beta-methylmalate synthase; EC 2.3.3.-; Citrate lyase subunit beta-like protein; Citrate lyase beta-like; Malate synthase; EC 2.3.3.9
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