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The antibody against CNGB1 was raised in rabbit using the Recombinant Human Cyclic nucleotide-gated cation channel beta-1 protein (131-253AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against CNGB1 was raised in rabbit using the Recombinant Human Cyclic nucleotide-gated cation channel beta-1 protein (131-253AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
$299.00
| Cat.No | ADC-04888A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CNGB1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Cyclic nucleotide-gated cation channel beta-1 protein (131-253AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q14028 |
Uniprot Id
Q14028
Target Species
Human
Target Name
CNGB1
Target Full Name
Cyclic nucleotide-gated channel beta-1
Target Function
Subunit of cyclic nucleotide-gated (CNG) channels, nonselective cation channels, which play important roles in both visual and olfactory signal transduction. When associated with CNGA1, it is involved in the regulation of ion flow into the rod photoreceptor outer segment (ROS), in response to light-induced alteration of the levels of intracellular cGMP.; Isoform GARP2 is a high affinity rod photoreceptor phosphodiesterase (PDE6)-binding protein that modulates its catalytic properties: it is a regulator of spontaneous activation of rod PDE6, thereby serving to lower rod photoreceptor 'dark noise' and allowing these sensory cells to operate at the single photon detection limit.
Target Involvement
Retinitis pigmentosa 45 (RP45)
Target Subcellular Location
Membrane; Multi-pass membrane protein.
Target Protein Families
Cyclic nucleotide-gated cation channel (TC 1.A.1.5) family, CNGB1 subfamily
Target Synonyms
CNGB1; CNCG2; CNCG3L; CNCG4; RCNC2Cyclic nucleotide-gated cation channel beta-1; Cyclic nucleotide-gated cation channel 4; CNG channel 4; CNG-4; CNG4; Cyclic nucleotide-gated cation channel gamma; Cyclic nucleotide-gated cation channel modulatory subunit; Cyclic nucleotide-gated channel beta-1; CNG channel beta-1; Glutamic acid-rich protein; GARP
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