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Rabbit anti-Human COL12A1 Polyclonal Antibody

The antibody against COL12A1 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human COL12A1. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on IHC, IF, ELISA.

ADC-36368A

The antibody against COL12A1 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human COL12A1. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on IHC, IF, ELISA.

$167.00

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Specifications


Cat.No ADC-36368A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCOL12A1
Target SynonymsCOL12A1 antibody; COL12A1LCollagen alpha-1(XII) chain antibodyFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerolPurification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ConjugateNon-conjugatedApplicationELISA, IF, IHC
StorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from the Internal region of Human COL12A1.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ99715
Background Information
  • Uniprot Id

    Q99715

  • Target Species

    Human

  • Target Name

    COL12A1

  • Target Full Name

    Collagen alpha-1(XII) chain

  • Target Function

    Type XII collagen interacts with type I collagen-containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix.

  • Target Involvement

    Ullrich congenital muscular dystrophy 2 (UCMD2); Bethlem myopathy 2 (BTHLM2)

  • Target Subcellular Location

    Secreted, extracellular space, extracellular matrix.

  • Target Protein Families

    Fibril-associated collagens with interrupted helices (FACIT) family

  • Target Tissue Specificity

    Found in collagen I-containing tissues: both isoform 1 and isoform 2 appear in amnion, chorion, skeletal muscle, small intestine, and in cell culture of dermal fibroblasts, keratinocytes and endothelial cells. Only isoform 2 is found in lung, placenta, ki

  • Target Research Area

    Signal Transduction

  • Target Synonyms

    COL12A1; COL12A1LCollagen alpha-1(XII) chain

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