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Rabbit anti-Human COL8A1 Polyclonal Antibody

The antibody against COL8A1 was raised in rabbit using the Human COL8A1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

ADC-48895A

The antibody against COL8A1 was raised in rabbit using the Human COL8A1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

$600.00

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Specifications


Cat.No ADC-48895A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCOL8A1
Target SynonymsC3orf7 antibody; CO8A1_HUMAN antibody; COL8A1 antibody; Collagen alpha 1(VIII) chain [Precursor] antibody; Endothelial collagen antibody; MGC9568 antibody; Vastatin antibodyFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azidePurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman COL8A1Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP27658
Background Information
  • Uniprot Id

    P27658

  • Target Species

    Human

  • Target Name

    COL8A1

  • Target Full Name

    Collagen alpha-1(VIII) chain

  • Target Function

    Macromolecular component of the subendothelium. Major component of the Descemet's membrane (basement membrane) of corneal endothelial cells. Also component of the endothelia of blood vessels. Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis.; Vastatin, the C-terminal fragment comprising the NC1 domain, inhibits aortic endothelial cell proliferation and causes cell apoptosis.

  • Target Subcellular Location

    Secreted, extracellular space, extracellular matrix, basement membrane.

  • Target Tissue Specificity

    Expressed primarily in the subendothelium of large blood vessels. Also expressed in arterioles and venules in muscle, heart, kidney, spleen, umbilical cord, liver and lung and is also found in connective tissue layers around hair follicles, around nerve b

  • Target Research Area

    Cardiovascular

  • Target Synonyms

    C3orf7; CO8A1_HUMAN; COL8A1; Collagen alpha 1(VIII) chain [Precursor]; Endothelial collagen; MGC9568; Vastatin

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